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[Characteristics of the antibiotic sensitivity of the pathogenic enterobacteria isolated from sick children]
Insights
Pathogenic enteric bacteria from children show low sensitivity to common antibiotics like levomycetin and tetracycline. This multiple antibiotic resistance necessitates careful treatment considerations for infected children.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Context:
- Pediatric infections caused by enteric bacteria are a significant public health concern.
- Emerging antibiotic resistance in pathogens like Shigella, enteropathogenic Escherichia, and Salmonella complicates treatment strategies.
- Understanding the sensitivity patterns of locally isolated strains is crucial for effective therapeutic interventions.
Purpose:
- To assess the antibiotic sensitivity profiles of pathogenic enteric bacteria isolated from children.
- To evaluate the effectiveness of commonly used antibiotics against these pediatric isolates.
- To inform clinical decision-making regarding antibiotic therapy for enteropathogenic infections in children.
Summary:
- A study analyzed 2287 strains of Shigella, enteropathogenic Escherichia, and Salmonella from children.
- These strains exhibited low sensitivity to widely used antibiotics including levomycetin, tetracycline, streptomycin, monomycin, neomycin, kanamycin, and erythromycin.
- Multiple antibiotic resistance was a significant finding in the studied bacterial isolates.
Impact:
- Highlights the challenge of treating pediatric enteric infections due to widespread antibiotic resistance.
- Underscores the need for clinicians to consider the observed multiple antibiotic sensitivities when selecting treatments.
- Suggests potential need for updated treatment guidelines or alternative therapeutic approaches for resistant enteropathogenic bacteria in pediatric populations.
Abstract:
The authors studied 2287 strains of pathogenic enteric bacteria, i.e. Shigella, enteropathogenic Escherichia and Salmonella freshly isolated from children with respect to their sensitivity to the most widely used antibiotics, i.e. levomycetin, tetracycline, streptomycin, monomycin, neomycin, kanamycin and erythromycin. Low sensitivity of these strains to the above antibiotics and their combinations was observed. In the treatment of children of this group it is necessary to take into account multiple antibiotic sensitivity of the isolates of the enteropathogenic bacteria.