Related Experiment Videos
Macrosphelide, a novel inhibitor of cell-cell adhesion molecule. II. Physiochemical properties and structural
S Takamatsu1, Y P Kim, M Hayashi
1The Kitasato Institute, Tokyo, Japan.
The Journal of Antibiotics
|January 1, 1996
Abstract:
New anticell-adherence compounds, macrosphelides A and B, were isolated from the fermentation broth of Microsphaeropis sp. FO-5050, and their structures were elucidated by spectroscopic methods and chemical transformations. Macrosphelides A (M.W. 342, C16H22O8) and B (M.W. 340, C16H20O8) with three esters in their molecules were classified as 16-membered macrocyclic compounds. Macrosphelide B was found to be a corresponding oxidative product of macrosphelide A at the C-14 position.