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Function of the upper extremities in hereditary multiple exostoses

R P Stanton1, M O Hansen

  • 1Alfred I. duPont Institute, Wilmington, Delaware 19899, USA.

The Journal of Bone and Joint Surgery. American Volume
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Hereditary multiple exostoses (HME) patients show minimal functional loss in upper extremities despite deformities. Impairment ratings averaged 5%, with most extremities functioning well long-term.

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Area of Science:

  • Orthopedics
  • Genetics
  • Rehabilitation Medicine

Background:

  • Hereditary multiple exostoses (HME) is a genetic disorder characterized by bone overgrowths.
  • Upper extremity involvement is common, but functional outcomes are not well-defined.

Purpose of the Study:

  • To evaluate radiographic anatomy, functional status, and impairment ratings in HME patients.
  • To correlate clinical findings with functional assessments.

Main Methods:

  • Retrospective review of 28 HME patients (56 extremities).
  • Radiographic assessment, subjective functional grading, and objective hand function tests (Jebsen et al.).
  • Analysis of impairment ratings and correlation with clinical variables.

Main Results:

  • Degenerative joint disease in 5% of extremities by average age 21.
  • Average hand test scores at 47th (dominant) and 28th (non-dominant) percentiles.
  • Radial head dislocation linked to negative ulnar variance and higher impairment ratings.
  • Whole-person impairment averaged 5% (range 0-17%).

Conclusions:

  • Upper extremity deformities in HME are generally well-tolerated.
  • Subjective and objective functional loss is minimal in most HME patients.
  • Specific radiographic findings correlate with impairment but not overall function.