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Recurrent corneal ulcerations associated with smokeable methamphetamine abuse
R S Chuck1, J M Williams, M A Goldberg
1Department of Ophthalmology and Visual Sciences, Washington University, MO 63110, USA.
Purpose:
We studied a case of chronic, recurrent, bilateral, corneal ulcerations associated with smokeable methamphetamine abuse, commonly known as "ice," in an otherwise healthy 31-year-old woman.
Methods:
Every few months the patient had recurrent corneal ulcerations. Each time, she was hospitalized and treated successfully with topical antibiotics.
Results:
Even though she had undergone numerous formal attempts at drug rehabilitation, she continued to have relapses, and ulceration recurred only during periods of smokeable methamphetamine abuse.
Conclusion:
Illicit use of smokeable methamphetamine may result in corneal ulceration.
Insights
Methamphetamine abuse, known as "ice," can cause chronic, recurring corneal ulcerations. This case highlights the link between illicit drug use and severe eye conditions.
Area of Science:
- Ophthalmology
- Toxicology
- Addiction Medicine
Background:
- Chronic, recurrent corneal ulcerations present a significant clinical challenge.
- Identifying underlying causes is crucial for effective patient management.
Observation:
- A 31-year-old woman experienced recurrent bilateral corneal ulcerations.
- Ulcerations consistently coincided with periods of smokeable methamphetamine (ice) abuse.
Findings:
- Despite multiple rehabilitation attempts, relapses occurred, correlating with methamphetamine use.
- Topical antibiotics successfully treated ulcerations during hospitalizations, but recurrence persisted with continued abuse.
Implications:
- This case suggests a direct association between smokeable methamphetamine use and corneal ulceration.
- Ophthalmologists and addiction specialists should consider methamphetamine abuse in patients with unexplained corneal issues.
- Further research is warranted to understand the pathophysiology and develop targeted interventions.
