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Protein B: an important human IgA-binding reagent

M A Grundy1, M S Blake, K Murray

  • 1Blake Laboratories Corporation, Great Neck, New York 11021, USA.

Protein B had a much higher affinity for human IgA than Jacalin, increasing the sensitivity and specificity of the measurement of total human IgA. Protein B, used as a capturing agent, greatly enhanced the measurement of antigen-specific IgA as compared to alpha chain-specific antibodies.

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