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Left ventricular endomyocardial fibrosis in India
British Heart Journal
|May 1, 1977
Summary
This study details left ventricular endomyocardial fibrosis in 8 patients, highlighting exertional dyspnea and characteristic heart sounds. Findings reveal impaired left ventricular function and pulmonary hypertension, crucial for understanding this rare cardiac condition.
Area of Science:
- Cardiology
- Cardiovascular Diseases
- Internal Medicine
Background:
- Left ventricular endomyocardial fibrosis is a rare cardiac condition.
- Understanding its clinical and hemodynamic features is essential for diagnosis and management.
Purpose of the Study:
- To describe the clinical, radiological, electrocardiographic, hemodynamic, and cineangiographic features of left ventricular endomyocardial fibrosis.
- To characterize the presentation and progression of the disease in a cohort of patients.
Main Methods:
- Retrospective analysis of 8 patients diagnosed with left ventricular endomyocardial fibrosis between 1965 and 1975.
- Review of clinical data, chest X-rays, electrocardiograms, hemodynamic measurements, and left ventriculography.
Main Results:
- Exertional dyspnea was the most common symptom.
- Characteristic findings included cardiomegaly, a loud third heart sound, and an apical systolic murmur.
- Hemodynamic data revealed elevated left ventricular end-diastolic pressure, pulmonary hypertension, and low cardiac index in most patients.
- Ventriculography demonstrated impaired left ventricular contraction and increased end-systolic volume.
Conclusions:
- Left ventricular endomyocardial fibrosis presents with distinct clinical and hemodynamic abnormalities.
- Characteristic auscultatory findings and imaging features aid in diagnosis.
- The disease is associated with significant left ventricular dysfunction and elevated pulmonary pressures.