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Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain
M S Nielsen1, C M Petersen, J Gliemann
1Department of Medical Biochemistry, University of Aarhus, Denmark. msn@biobase.dk
Biochimica Et Biophysica Acta
|April 10, 1996
Abstract:
A 2985 bp cDNA was isolated from a Lambda Zap Express library and sequenced. The cDNA appeared to represent a previously unknown gene that encodes and acidic 757 amino acid protein containing a bromodomain, several potential sites for phosphorylation by casein kinase-II and small proline-rich segments. The results suggest that the encoded protein might be a novel transcription factor.