Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thalassemia in pregnancy

S J Kilpatrick1, R K Laros

  • 1Department of Ob-Gyn and Reproductive Sciences, University of California at San Francisco, 94143-0132, USA.

Clinical Obstetrics and Gynecology
|September 1, 1995
PubMed
Summary

Obstetricians should screen women for thalassemia carriers in the first trimester. If the father is also a carrier, prenatal diagnosis offers couples reproductive choices.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impending macrosomia: will induction of labour modify the risk of caesarean delivery?

BJOG : an international journal of obstetrics and gynaecology·2012
Same author

Outcomes associated with cesarean section versus vaginal breech delivery at a university hospital.

Journal of perinatology : official journal of the California Perinatal Association·2006
Same author

Fetal acidemia and electronic fetal heart rate patterns: is there evidence of an association?

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2006
Same author

A descriptive model of preventability in maternal morbidity and mortality.

Journal of perinatology : official journal of the California Perinatal Association·2006
Same author

Effect of chondrocalcinosis on the MR imaging of knee menisci.

AJR. American journal of roentgenology·2001
Same author

When parents reject interventions to reduce postnatal human immunodeficiency virus transmission.

Archives of pediatrics & adolescent medicine·2001

Area of Science:

  • Obstetrics and Gynecology
  • Medical Genetics
  • Prenatal Diagnosis

Background:

  • Thalassemia is a genetic blood disorder requiring early identification.
  • Carrier screening is crucial for reproductive planning in affected populations.

Purpose of the Study:

  • To outline the obstetrician's role in identifying thalassemia carriers.
  • To emphasize the importance of partner screening and genetic counseling.
  • To highlight the availability and utility of prenatal diagnosis for thalassemia.

Main Methods:

  • First-trimester screening of pregnant women for thalassemia carrier status.
  • Screening of the male partner if the female is identified as a carrier.
  • Offering prenatal diagnostic testing to at-risk couples.

Main Results:

  • Identification of carrier status allows for targeted genetic counseling.
  • Prenatal diagnosis can detect homozygous thalassemia fetuses.
  • Families are empowered with reproductive choices based on diagnostic results.

Conclusions:

  • Early identification of thalassemia carriers by obstetricians is essential.
  • Partner screening and prenatal diagnosis are key components of thalassemia management.
  • Prenatal diagnosis provides crucial information for family planning decisions.

Related Experiment Videos