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Updated: Aug 17, 2026

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
Published on: April 2, 2013
Spectrum of Legionella species whose intracellular multiplication in murine macrophages is genetically controlled by
H Miyamoto1, K Maruta, M Ogawa
1Department of Microbiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract:
We examined the intracellular growth of 20 strains within six species of Legionella in thioglycolate-elicited peritoneal macrophages from A/J and C57BL/6 mice and a congenic strain derived from them (A.B Lgn1). With the exception of Legionella pneumophila Togus-1 and Bloomington-2, the intracellular growth of the 15 L. pneumophila strains tested was controlled by Lgn1. However, the intracellular growth of five Legionella species other than L. pneumophila was not under Lgn1's control.

