Related Experiment Videos
Acquired cerebral arteriovenous malformation in a child with moyamoya disease. Case report
B P Schmit1, P E Burrows, K Kuban
1Department of Radiology, Children's Hospital, Boston, Massachusetts 02115, USA.
Abstract:
The authors report a unique case involving a 2-year-old child with idiopathic moyamoya disease who presented with cerebral infarctions and seizures. On initial evaluation, computerized tomography (CT) showed a left parietal infarct and angiograms demonstrated early moyamoya disease with no evidence of arteriovenous malformation (AVM). Approximately 9 years later, angiography and magnetic resonance (MR) imaging revealed an AVM centered on the same region of the left parietal lobe. Angiographic, CT, and MR images are presented that demonstrate the progression of moyamoya disease and de novo development of the AVM in the infarct site. The possible role of angiogenesis in the etiology of acquired AVMs and moyamoya disease is discussed.
Insights
This case study details a child with moyamoya disease who developed an arteriovenous malformation (AVM) at an infarct site. It highlights the potential role of angiogenesis in acquired AVMs and moyamoya disease progression.
Area of Science:
- Neurology
- Vascular Medicine
- Pediatric Neurology
Background:
- Moyamoya disease is a rare, progressive cerebrovascular disorder.
- Cerebral infarctions and seizures are common initial presentations in pediatric moyamoya disease.
- The de novo development of arteriovenous malformations (AVMs) in the context of moyamoya disease is not well-documented.