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Tumoral calcinosis: radiologic-pathologic correlation
L S Steinbach1, J O Johnston, E F Tepper
1Department of Radiology, University of California San Francisco 94143, USA.
Skeletal Radiology
|November 1, 1995
Summary
Tumoral calcinosis, often misdiagnosed, presents distinct radiologic features. Key findings include dense calcified masses with a "chicken wire" pattern, aiding differentiation from other calcified lesions.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Tumoral calcinosis is a rare condition characterized by calcium deposits.
- It is frequently misdiagnosed due to overlapping features with other calcified lesions.
- Accurate diagnosis relies on understanding its unique radiologic and pathologic characteristics.
Purpose of the Study:
- To detail the radiologic and pathologic features of tumoral calcinosis.
- To differentiate tumoral calcinosis from other calcified lesions.
- To improve diagnostic accuracy for tumoral calcinosis.
Main Methods:
- Review of radiologic and pathologic findings from 12 tumoral calcinosis patients.
- Comparison with 5 patients with other calcified lesions.
- Analysis of medical records for patient demographics and clinical history.
Main Results:
- Tumoral calcinosis showed dense, homogeneous calcified masses with a "chicken wire" pattern of lucencies.
- Histology correlated lucencies with thin fibrous septae.
- Fluid-calcium levels and smooth osseous erosions were observed in some cases.
- Retrospective analysis confirmed characteristic radiologic findings despite initial misdiagnosis in 5 cases.
Conclusions:
- The "chicken wire" pattern is a consistent radiologic hallmark of tumoral calcinosis.
- Associated features like fluid-calcium levels and osseous erosions further support the diagnosis.
- Radiologic and pathologic correlation is crucial for distinguishing tumoral calcinosis from mimics.