Probable transfusion-associated graft-versus-host disease in a patient with tuberous sclerosis

Acute transfusion-associated graft-versus-host disease (TA-GVHD) is rare but often fatal. Graft-versus-host disease that occurs as a complication of bone marrow transplantation is more common but has lower mortality. Features of TA-GVHD are nonspecific and can be confused with viral infections and drug reactions. We present a case of probable TA-GVHD in a patient with tuberous sclerosis who survived and was subsequently given irradiated blood without any further adverse events.