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Salivary factors in caries models

D I Hay1

  • 1Department of Biochemistry, Forsyth Dental Center, Boston, MA 02115, USA.

Advances in Dental Research
|November 1, 1995
PubMed
Summary

Saliva

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Area of Science:

  • Biochemistry
  • Microbiology
  • Dental Science

Background:

  • Traditional dental caries models often overlook saliva's complex biochemical roles.
  • Saliva's functions extend beyond simple buffering and dilution of plaque acids.

Purpose of the Study:

  • To highlight the multifaceted impact of salivary factors on dental plaque.
  • To advocate for the inclusion of detailed salivary activities in caries modeling.

Main Methods:

  • Review of existing literature on salivary composition and function.
  • Analysis of biochemical and microbiological interactions between saliva and plaque.

Main Results:

  • Saliva provides essential microbial nutrients, influencing bacterial acid production.
  • Salivary components affect buffering capacity, calcium phosphate precipitation, and enamel pellicle formation.
  • Saliva's antimicrobial properties and microbial adaptations within plaque are significant but understudied.

Conclusions:

  • Saliva's complex chemistry and biochemical activities profoundly influence plaque.
  • Accurate dental caries models must incorporate the diverse roles of saliva.
  • Further research is needed on microbial adaptations to salivary antimicrobial systems.

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