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Related Experiment Videos

Screening for abdominal aortic aneurysm: a computer assisted cost-utility analysis

A S St Leger1, M Spencely, C N McCollum

  • 1School of Epidemiology and Health Sciences, University of Manchester, UK.

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
|February 1, 1996
PubMed
Summary

Routine screening for abdominal aortic aneurysms (AAA) in men aged 65-74 is cost-effective. Screening for AAAs greater than or equal to 6 cm offers a favorable cost per quality-adjusted life year (QALY) compared to other health services.

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Area of Science:

  • Vascular Surgery
  • Health Economics
  • Public Health Screening

Background:

  • Abdominal aortic aneurysms (AAA) pose a significant rupture risk.
  • Early detection and elective surgical treatment improve outcomes.
  • Routine screening programs aim to identify high-risk individuals.

Purpose of the Study:

  • To evaluate the cost-effectiveness of routine ultrasonic screening for AAA in UK men aged 65-74.
  • To assess the impact of screening on identifying AAAs at high risk of rupture.
  • To compare the cost per quality-adjusted life year (QALY) gained with existing health services.

Main Methods:

  • Computer-assisted simulation of an AAA screening program.
  • Incorporation of literature-based epidemiology and screening costs.

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  • Utilisation of recent vascular surgery cost data.
  • Dialogue exploring feasibility with NHS commissioners and providers.

    • Main Results:

    • Screening for AAAs ≥ 6 cm yielded an absolute cost of £1500 per QALY gained (undiscounted benefit).
    • Net additional cost per QALY was £1300 after offsetting current ruptured aneurysm treatment costs.
    • Screening for AAAs ≥ 5 cm exceeded £20,000 per QALY gained.
    • Findings remained robust under sensitivity analysis.

    Conclusions:

    • Routine screening for AAAs ≥ 6 cm is a cost-effective intervention.
    • The cost per QALY gained compares favorably with breast and cervical cancer screening programs.
    • Selective screening for larger aneurysms offers better economic value.