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Inducible nitric oxide synthase gene expression in the brain during systemic inflammation

M L Wong1, V Rettori, A al-Shekhlee

  • 1Clinical Neuroendocrinology Branch, National Institutes of Mental Health, National Institutes of Health, Bethesda, Maryland 20892-1284, USA.

Nature Medicine
|May 1, 1996
PubMed
Summary

Systemic inflammation induces inducible nitric oxide synthase (iNOS) in the brain, producing nitric oxide (NO). Nitrite in cerebrospinal fluid may serve as a diagnostic marker for sepsis.

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