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Pemphigus vulgaris--the potential for error: a case report
M Harel-Raviv1, H Srolovitz, M Gornitsky
1Department of Preventive & Community Dentistry, Faculty of Dentistry, McGill University, Montreal, Quebec, Canada.
Summary
Accurate biopsy is crucial for diagnosing pemphigus vulgaris, preventing misdiagnosis as actinic keratosis. Collaboration between dermatology and oral health professionals ensures correct patient management and treatment.
Area of Science:
- Oral Medicine
- Dermatology
- Pathology
Background:
- Pemphigus vulgaris can present with oral lesions that may be misdiagnosed.
- Delayed diagnosis can result from inadequate or improper biopsy procedures.
- Interdisciplinary collaboration is essential for accurate diagnosis and treatment.
Observation:
- A case of pemphigus vulgaris was diagnosed via tongue biopsy and confirmed with immunofluorescence.
- The patient initially received treatment for actinic keratosis for 16 months due to insufficient biopsy material.
- Clinical features of pemphigus vulgaris can mimic actinic keratosis, leading to diagnostic challenges.
Findings:
- Proper biopsy material is critical for the definitive diagnosis of pemphigus vulgaris.
- Immunofluorescence confirmed the pemphigus vulgaris diagnosis.
- The case highlights diagnostic pitfalls due to inadequate biopsy sampling.
Implications:
- Emphasizes the need for adequate biopsy techniques in diagnosing mucocutaneous diseases.
- Highlights the importance of correlating clinical presentation with histopathological findings.
- Underscores the value of collaboration between dermatology and oral health specialists for improved patient outcomes.