Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphologic changes in pulmonary vasculature with arteriographic correlation

S Basu1, B N Datta, N Khandelwal

  • 1Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Angiology
|April 1, 1996
PubMed
Summary

Pulmonary vasculature undergoes rapid structural remodeling after birth, with medial thickness decreasing significantly within the first month. This change stabilizes by one month and remains consistent until age fourteen.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic Utility of Automated Breast Volume Scan in Differentiating Benign and Malignant Breast Masses.

Cureus·2025
Same author

Cardiac dysfunction in transfusion-dependent β-thalassaemia: Insights into apolipoprotein E genotypes and iron metrics in a north Indian cohort.

British journal of haematology·2025
Same author

Predatory Journals: "The Gray Market" of Academic Publishing.

The Indian journal of radiology & imaging·2025
Same author

Exposure to <i>Toxocara Canis</i> is not Associated with New-Onset Epilepsy.

Neurology India·2022
Same author

Ruptured cerebral aneurysm in isolated type A interrupted aortic arch managed by transradial endovascular route: A case report with literature review.

The neuroradiology journal·2022
Same author

Veliparib monotherapy following carboplatin/paclitaxel plus veliparib combination therapy in patients with germline BRCA-associated advanced breast cancer: results of exploratory analyses from the phase III BROCADE3 trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2021

Area of Science:

  • Cardiovascular Physiology
  • Pediatric Pathology
  • Pulmonary Vascular Remodeling

Background:

  • The fetal pulmonary circulation maintains high resistance.
  • Postnatal breathing initiates sequential structural changes in pulmonary vasculature.
  • Existing literature presents varied findings on pulmonary vascular remodeling.

Purpose of the Study:

  • To delineate the structural changes in pulmonary vasculature following birth.
  • To quantify alterations in arterial morphology in children up to fourteen years of age.

Main Methods:

  • Autopsy cases (n=25) from newborns to 14-year-olds were analyzed.
  • Postmortem arteriography was performed in most cases.
  • Histomorphometry was utilized to quantify arterial morphology.

Related Experiment Videos

Main Results:

  • Newborn pulmonary arteries exhibit a thick-walled structure.
  • Medial thickness significantly reduces within one month post-birth, most rapidly in the first three days.
  • No significant changes in medial thickness were observed between one month and fourteen years of age.

Conclusions:

  • Pulmonary vascular remodeling post-birth is characterized by a rapid reduction in medial thickness within the first month.
  • This medial thickness stabilizes after the first month and remains consistent throughout childhood up to 14 years.
  • Understanding these changes is crucial for pediatric cardiovascular health.