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Teething and acute graft vs. host disease: a clinical observation
1Department of Pediatric Dentistry, Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
The Journal of Clinical Pediatric Dentistry
|January 1, 1996
Abstract:
A 5-month-old girl, treated with bone marrow transplantation for severe combined immunodeficiency, developed two episodes of severe acute graft vs. host disease (GVHD) while teething. A dramatic improvement in GVHD was noted after the completion of tooth eruption. It is suggested that the release of interleukin-1, associated with the traumatized gingival tissue, is the triggering mediator for the GVHD.