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[Selected cell-mediated immunologic parameters in patients with intrinsic asthma treated with long-term
T Moniuszko1, R Rutkowski, S Chyrek-Borowska
1Kliniki Alergologii AM w Białymstoku.
Pneumonologia I Alergologia Polska
|January 1, 1995
Abstract:
Total lymphocytes number, proportions of T lymphocyte subset, nonspecific suppressor activity induced by Con A and T-lymphocytes ability for IL-2 production were assessed. Group of 46 patients with intrinsic asthma (24 females and 22 males) including 20 asthmatics treated during 5-7 years with glucocorticosteroids were studied. Control group consisted of 12 healthy persons. Statistically significant reduction of total T cells, T-suppressor and T-helper subpopulations, ability for IL-2 production and nonspecific suppressor activity was found.