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Cloning the gene encoding Schistosoma mansoni p50, an immunophilin
D Kiang1, A M Karim, P T LoVerde
1Department of Microbiology, State University of New York, Buffalo 14214, USA.
Gene
|April 17, 1996
Abstract:
A 2.2-kb fragment of genomic DNA encoding Schistosoma mansoni immunophilin p50 (Smp50) was identified on a 14-kb genomic clone. The sequence of Smp50 reveals seven exons interrupted by six small introns ranging from 28-35 bp in size. The transcription start point, defined by primer extension analysis of schistosome RNA, begins at 30 bp upstream from the start AUG codon. Smp50 lacks a TATA box and appears to be a single-copy gene.