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Different action of xenoreactive natural and immune antibodies on functioning cardiomyocytes

A Autenrieth1, U Müller-Werdan, B Koidl

  • 1Institute for Surgical Research, Grosshadern, Ludwig-Maximilians-University, Munich, Germany.

PNAB and IAB have totally different action on BCM. PNAB inhibit the contractile function of BCM by producing a reversible standstill and by disturbing the synchronization of the BCM-monolayer. IAB are cytotoxic and depend on the presence of complement.

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