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Related Experiment Videos

Malalignment-type ventricular septal defect in double-chambered right ventricle

J K Wang1, M H Wu, C I Chang

  • 1Department of Pediatric, National Taiwan University Hospital, Taipei, Taiwan.

The American Journal of Cardiology
|April 15, 1996
PubMed
Summary

Double-chambered right ventricle (DCRV) is often linked to ventricular septal defect (VSD). This study found malalignment-type VSDs in DCRV are associated with higher pulmonary blood flow and subaortic ridges, impacting heart failure risk.

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Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Research
  • Cardiac Morphology and Hemodynamics

Background:

  • Double-chambered right ventricle (DCRV) is a congenital heart defect.
  • Ventricular septal defect (VSD) frequently co-occurs with DCRV.
  • The specific impact of malalignment-type VSD on DCRV characteristics requires further elucidation.

Purpose of the Study:

  • To investigate the association between malalignment-type VSD and hemodynamic/morphologic features in DCRV patients.
  • To compare clinical outcomes and anatomical variations between DCRV patients with and without malalignment-type VSD.

Main Methods:

  • Retrospective analysis of 53 DCRV patients over 8.5 years.
  • Utilized echocardiography, cardiac catheterization, and angiography for patient assessment.

Related Experiment Videos

  • Categorized patients into groups based on the presence (Group I) or absence (Group II) of malalignment-type VSD.

    • Main Results:

    • Congestive heart failure in infancy was significantly more prevalent in Group I (53%) compared to Group II (15%).
    • Group I exhibited a higher pulmonary-to-systemic flow ratio (1.89 vs 1.14) and a lower right ventricular outflow tract pressure gradient (41 vs 73 mm Hg).
    • A subaortic ridge was exclusively observed in 73% of Group I patients, while aortic valve prolapse and septal defect aneurysm formation showed no significant difference between groups.

    Conclusions:

    • Malalignment-type VSD is a significant factor in DCRV, correlating with increased pulmonary blood flow and the presence of a subaortic ridge.
    • DCRV patients with malalignment-type VSD have a higher incidence of infantile congestive heart failure.
    • These findings highlight the importance of identifying malalignment-type VSD in the management of DCRV.