Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone remodelling adjacent to intramedullary stems: an optimal structures approach

T P Harrigan1, J J Hamilton, J D Reuben

  • 1Department of Orthopedic Surgery, University of Texas Health Center at Houston 77030, USA.

Biomaterials
|January 1, 1996
PubMed
Summary

A simplified formula accurately predicts bone structure changes around implants, aiding understanding of bone remodeling and clinical applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multiscale orchestrated computational framework to reveal emergent phenomena in neuroblastoma.

Computer methods and programs in biomedicine·2023
Same author

Delivering computationally-intensive digital patient applications to the clinic: An exemplar solution to predict femoral bone strength from CT data.

Computer methods and programs in biomedicine·2021
Same author

Evaluation of patient tissue selection methods for deriving equivalent density calibration for femoral bone quantitative CT analyses.

Bone·2020
Same author

Effect of size and location of simulated lytic lesions on the structural properties of human vertebral bodies, a micro-finite element study.

Bone reports·2020
Same author

Predicting bone strength from CT data: Clinical applications.

Morphologie : bulletin de l'Association des anatomistes·2019
Same author

Investigating rolling as mechanism for humeral fractures in non-ambulant infants: a preliminary finite element study.

Clinical radiology·2019

Area of Science:

  • Biomechanics
  • Computational Biology
  • Orthopedic Surgery

Background:

  • Internal parameters in bone remodeling theories lack clear links to simulated bone structure.
  • Previous work established a connection between structural optimization and continuum-level remodeling rules.

Purpose of the Study:

  • To determine if a simplified analytical formula based on structural optimization can predict finite element bone remodeling simulations.
  • To provide a physical interpretation for parameters in bone remodeling rules.
  • To demonstrate a practical application of optimizing remodeling theory.

Main Methods:

  • Utilized a simplified analytical formula derived from structural optimization principles.
  • Employed a large-scale finite element bone remodeling simulation.

Related Experiment Videos

  • Used a numerically stable remodeling algorithm based on optimization.

    • Main Results:

    • The analytical formula successfully predicted bone preservation around an intramedullary implant.
    • Numerical simulation results confirmed the predictions of the analytical formula.
    • A physical interpretation for one parameter in the remodeling rule was established.

    Conclusions:

    • Simplified analytical formulas based on structural optimization can predict bone remodeling simulation outcomes.
    • The study provides clinical relevance by explaining bone behavior around implants.
    • This work extends previous findings on internal bone remodeling and offers practical applications for developed theories.