Related Experiment Videos
Total knee arthroplasty in tuberculous arthritis
1Department of Orthopaedic Surgery, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
Clinical Orthopaedics and Related Research
|February 1, 1996
Summary
Total knee arthroplasty can effectively treat knee tuberculosis, but preoperative chemotherapy is crucial. Patients not receiving pre-surgery treatment or those on corticosteroids face a higher risk of tuberculosis reactivation.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Rheumatology
Background:
- Tuberculosis (TB) can severely damage the knee joint.
- Total knee arthroplasty (TKA) is a surgical option for advanced knee destruction.
- The role of pre-operative chemotherapy in TKA for tuberculous arthritis is debated.
Purpose of the Study:
- To evaluate the outcomes of TKA in patients with knee tuberculosis.
- To assess the impact of pre-operative antituberculous chemotherapy on TKA success.
- To identify risk factors for TB recurrence after TKA.
Main Methods:
- Retrospective review of 16 patients undergoing TKA for knee tuberculosis.
- Analysis of pre-operative and post-operative antituberculous chemotherapy regimens.
- Assessment of functional knee scores and TB recurrence rates.
Main Results:
- TKA significantly improved functional knee scores (mean 30.5 to 82.6).
- Five cases (31%) experienced TB recurrence.
- Four of five recurrences occurred in patients without pre-operative chemotherapy.
- One case with corticosteroid dependency required excisional arthroplasty.
Conclusions:
- TKA is a viable treatment for severe knee tuberculosis.
- Effective pre-operative and post-operative chemotherapy is essential for successful TKA outcomes.
- Patients not treated pre-operatively or on corticosteroids have a high risk of TB reactivation.