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Osteosarcoma and Ewing's sarcoma in a retinoblastoma patient
R M Kay1, J J Eckardt, J M Mirra
1Department of Orthopaedic Surgery, University of California, Los Angeles School of Medicine, 90095-6902, USA.
Clinical Orthopaedics and Related Research
|February 1, 1996
Abstract:
Retinoblastoma, though uncommon, frequently is associated with other second malignant neoplasms, especially bone sarcomas. These second neoplasms can occur in sporadic cases of retinoblastoma, though they more commonly are associated with genetic forms of the disease. This is the first known report of 2 histologically distinct bone sarcomas in a patient with retinoblastoma.