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Pheochromocytoma associated with clinical and echocardiographic features simulating hypertrophic obstructive
K R Huddle1, B Kalliatakis, J Skoularigis
1Department of Medicine, Baragwanath Hospital, Johannesburg, South Africa.
Insights
Pheochromocytoma can cause left ventricular hypertrophy mimicking hypertrophic obstructive cardiomyopathy. Tumor removal relieved symptoms and normalized blood pressure and ECGs, but echocardiographic changes only partially regressed.
Area of Science:
- Cardiology
- Endocrinology
- Oncology
Background:
- Pheochromocytoma is a rare neuroendocrine tumor.
- Left ventricular hypertrophy (LVH) can be a complication of pheochromocytoma.
- LVH may mimic hypertrophic obstructive cardiomyopathy (HOCM).
Abstract:
Left ventricular hypertrophy simulating hypertrophic obstructive cardiomyopathy is a rare complication of pheochromocytoma. In this report, two cases of pheochromocytoma with this complication are described. Successful tumor removal in both cases led to relief of symptoms, normalization of BP, regression of abnormal clinical features, normalization of the ECGs, but only partial regression of the echocardiographic features despite prolonged follow-up of 24 and 32 months, respectively.