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Climatic droplet keratopathy in leprosy
1Department of Ophthalmology, Schieffelin Leprosy Research and Training Center, Karigiri, North Arcot District, Tamil Nadu, India.
Summary
A unique form of climatic droplet keratopathy (CDK) affects leprosy patients, particularly those with lepromatous leprosy. This corneal condition may involve nerve infection and is linked to reduced corneal sensation.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Dermatology
Background:
- Climatic droplet keratopathy (CDK) is a degenerative corneal condition.
- Leprosy, a chronic infectious disease, can affect various organs, including the eyes.
Purpose of the Study:
- To describe an atypical presentation of CDK in leprosy patients.
- To investigate the association between CDK and lepromatous leprosy.
- To explore potential mechanisms involving corneal nerves.
Main Methods:
- Case series describing 24 eyes from 17 leprosy patients with atypical CDK.
- Clinical examination of corneal lesions, location, and associated factors.
- Assessment of corneal sensation.
Main Results:
- Atypical CDK observed in the lower outer cornea, unrelated to trauma or scars.
- Most patients had lepromatous leprosy.
- Impaired corneal sensation noted in 15 of 24 affected eyes.
Conclusions:
- A distinctive form of CDK exists in lepromatous leprosy patients.
- Corneal nerve involvement and infection are potential factors.
- This presentation highlights a specific ocular manifestation of leprosy.