Related Experiment Videos
Characterization of long-term cultures of hepatitis C virus
N Nakajima1, M Hijikata, H Yoshikura
1Department of Bacteriology, Faculty of Medicine, University of Tokyo, Japan.
Journal of Virology
|May 1, 1996
Abstract:
The human T- and B-cell lines HPBMa10-2 and Daudi produced infectious hepatitis C virus (HCV) for more than 1 year after infection. The infectivity titer of the cell culture-grown HCV and its genome titer were comparable. The virion density in sucrose was around 1.12 g/ml. Among the 13 variants detected in the inoculum, 7 were adsorbed by the cells and one particular HCV sequence which was present in minor quantities in the inoculum persisted.