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Published on: November 25, 2022
[Leptospirosis at the Clinic for Infectious Diseases in Novi Sad 1984-1993]
G Canak1, Z Vukobratov, M Dordević
1Klinika za infektivne i dermatoveneroloske bolestic, Medicinski fakultet, Novi Sad.
Abstract:
We examined the clinical picture and course of leptospiral infections in 50 patients treated at the Clinic during the period 1984-1993. Most patients were 11-20 years of age (9 years the youngest and 77 years the oldest, mean age being 25.16). The disease more often occurred in male patients, 44 (88%). There were 30 (60%) patients with gastrointestinal symptoms, while 21 (42%) had liver and kidney infections. Meningeal syndrome was established in 25 (50%) and serous meningitis in 13 (26%). Leptospiral infections represented average and serious infections with complications in 8 (16%) patients, successful treatment in 47 (94%) patients while 3 (6%) patients died due to hematorenal insufficiency.
Insights
This study reviewed 50 cases of leptospirosis, a bacterial infection, noting its prevalence in young males and common gastrointestinal and organ-specific symptoms. Most patients recovered, but severe cases led to fatalities from kidney complications.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Medicine
Context:
- Leptospirosis is a zoonotic bacterial infection with a wide spectrum of clinical manifestations.
- Understanding the clinical presentation and outcomes is crucial for timely diagnosis and management.
Purpose:
- To analyze the clinical features, demographics, and outcomes of leptospiral infections in a patient cohort.
- To identify common symptoms, complications, and mortality factors associated with leptospirosis.
Summary:
- The study retrospectively analyzed 50 patients diagnosed with leptospirosis between 1984 and 1993.
- The majority of patients were young males, presenting with gastrointestinal issues, liver/kidney involvement, and meningeal syndromes.
- While 94% of patients experienced successful treatment, 6% succumbed to hematorenal insufficiency, highlighting the potential severity of the infection.
Impact:
- Provides insights into the clinical epidemiology of leptospirosis in the studied region.
- Emphasizes the importance of recognizing diverse clinical presentations for effective patient care.
- Highlights risk factors for severe outcomes and mortality in leptospiral infections.
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