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Five days of whole-bowel irrigation in a case of pediatric iron ingestion
1Department of Pediatrics, University of Rochester School of Medicine, New York, USA.
Insights
This case study shows that high volumes of polyethylene glycol electrolyte solution (PEG-ELS) can be safely used for whole-bowel irrigation in pediatric iron poisoning. The treatment effectively cleared the gastrointestinal tract without adverse effects.
Area of Science:
- Toxicology
- Gastroenterology
- Emergency Medicine
Background:
- The safe limits for polyethylene glycol electrolyte solution (PEG-ELS) in whole-bowel irrigation for poisoned patients are not well-established.
- Whole-bowel irrigation is a decontamination procedure used in toxicology.
Purpose of the Study:
- To report a case of a pediatric patient who received an exceptionally large volume and duration of PEG-ELS for iron poisoning.
- To assess the safety and efficacy of high-volume PEG-ELS therapy in this context.
Main Methods:
- A 33-month-old boy ingested a significant amount of elemental iron.
- The patient underwent whole-bowel irrigation with 44.3 L of PEG-ELS over 5 days due to persistent iron tablets in the GI tract.
- Clinical status, iron absorption, and rectal effluent were monitored.
Main Results:
- The child tolerated the large volume (44.3 L, 2,953 ml/kg) and duration (5 days) of PEG-ELS without adverse effects.
- Rectal effluent cleared within 2 days, indicating successful gastrointestinal decontamination.
- No further significant iron absorption was observed despite persistent radiopaque material.
Conclusions:
- This case demonstrates that extensive volumes and durations of PEG-ELS can be safely administered for whole-bowel irrigation in pediatric iron poisoning.
- High-volume PEG-ELS therapy can be effective in managing persistent gastrointestinal contamination in toxic ingestions.
Abstract:
The maximum duration and volume of polyethylene glycol electrolyte solution (PEG-ELS) that can be safely administered during whole-bowel irrigation of the poisoned patient are poorly defined. We present a case of a 33-month-old boy who ingested at least 160 mg/kg elemental iron and received 44.3 L of PEG-ELS (2,953 ml/kg) over 5 days because of the persistence of iron tablets in teh gastrointestinal tract. The child remained clinically well after initiation of PEG-ELS therapy, and further significant iron absorption did not appear to occur. The rectal effluent cleared within 2 days of the start of PEG-ELS therapy despite the persistence of iron in the gastrointestinal tract as shown on radiography. No adverse effects resulted from teh large volume or duration of the PEG-ELS therapy. This is the greatest reported volume of PEG-ELS to be used for whole-bowel irrigation in the treatment of a toxic ingestion.
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