Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pressure ulcers in SCI: does tension stimulate wound healing?

B Goldstein1, J E Sanders, B Benson

  • 1Spinal Cord Injury Service, Seattle VA Medical Center, Seattle, Washington 98108, USA.

American Journal of Physical Medicine & Rehabilitation
|March 1, 1996
PubMed
Summary

Mechanical tension may accelerate wound healing in pressure ulcers. Studies suggest that applying tension to nonhealing wounds, particularly in older and disabled individuals, can stimulate tissue repair and promote faster recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Peripartum cardiomyopathy: A review of the literature].

Gynecologie, obstetrique, fertilite & senologie·2021
Same author

Umbilical Cord-derived Mesenchymal Stem Cells for COVID-19 Patients with Acute Respiratory Distress Syndrome (ARDS).

CellR4-- repair, replacement, regeneration, & reprogramming·2021
Same author

Implementing a declination form programme to improve influenza vaccine uptake by staff in Department of Veterans Affairs spinal cord injury centres: a pilot study.

The Journal of hospital infection·2015
Same author

Noise analysis and performance comparison of low current measurement systems for biomedical applications.

IEEE transactions on biomedical circuits and systems·2013
Same author

Lack of resveratrol neuroprotection in developing rats treated with kainic acid.

Neuroscience·2012
Same author

Applications of accelerator MS in pediatric drug evaluation.

Bioanalysis·2012

Area of Science:

  • Biomedical Engineering
  • Wound Healing Research
  • Tissue Repair Mechanisms

Background:

  • Pressure ulcers pose significant challenges for older and disabled populations.
  • Existing research extensively covers pressure ulcer etiology and epidemiology but lacks detail on tissue repair stimulation.
  • The impact of mechanical stress on wound healing remains under-investigated, especially for tissues under high mechanical load.

Observation:

  • Areas like perineal tissues experience substantial mechanical forces.
  • Two case studies from the Seattle VAMC demonstrated nonhealing myocutaneous flap wounds.
  • These wounds healed rapidly within two weeks after implementing a range-of-motion program.

Findings:

  • The case studies support the hypothesis that mechanical tension can stimulate wound healing.

Related Experiment Videos

  • Initiating a range-of-motion program applying tension to nonhealing flaps led to accelerated closure.
  • This suggests tension is a viable factor in promoting tissue repair.

    • Implications:

    • Mechanical stress, specifically tension, may be a critical factor in enhancing wound healing.
    • Therapeutic strategies involving controlled mechanical tension could be developed for pressure ulcer treatment.
    • Further research into the biomechanics of wound healing is warranted to optimize patient outcomes.