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Carcinomatous meningitis complicating cervical cancer: a clinicopathologic study and literature review
D M Aboulafia1, L P Taylor, R D Crane
1Division of Hematology/Oncology, Virginia Mason Medical Center, Seattle, Washington 98111, USA.
Abstract:
Patients with gynecologic malignancies may develop metastases throughout the neuraxis. Cervix-related carcinomatous meningitis is a distinctly unusual clinical event with only two previous cases reported in the English medical literature. We review clinical, radiographic, and pathologic findings of a woman with advanced adenocarcinoma of the uterine cervix, whose course was complicated by leptomeningeal metastases. Carcinomatous meningitis occurs in the setting of rapidly advancing systemic disease and represents a terminal complication of cervical cancer.
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