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Transitional cell carcinoma of the endometrium
G W Spiegel1, R M Austin, P L Gelven
1Department of Pathology, Medical University of South Carolina, Charleston 29425, USA.
Gynecologic Oncology
|February 1, 1996
Summary
This report details a second case of endometrial transitional cell carcinoma (TCC), a rare cancer. Both patients with this rare endometrial cancer survived over five years after radiation therapy.
Area of Science:
- Gynecologic Oncology
- Pathology
- Radiation Oncology
Background:
- Endometrial transitional cell carcinoma (TCC) is an exceptionally rare malignancy.
- Only one prior case of endometrial TCC has been documented in medical literature.
Observation:
- This report presents the second documented case of endometrial TCC.
- In both this case and the previously reported case, a distinct focus of TCC was identified in the adnexa.
Findings:
- Both patients received adjuvant whole pelvic radiation therapy.
- Both patients remain alive and disease-free at 5 years and 15 months post-treatment, respectively.
Implications:
- Further investigation into additional endometrial TCC cases is warranted.
- Determining if endometrial TCC exhibits a superior response to radiation compared to other endometrial carcinomas with extrauterine spread is crucial.