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Erythromycin-induced acute pancreatitis
Journal of Toxicology. Clinical Toxicology
|January 1, 1996
Summary
Erythromycin, an antibiotic, can rarely cause acute pancreatitis. This case report details a patient who developed pancreatitis after taking a high dose of erythromycin and recovered with supportive care.
Area of Science:
- Pharmacology
- Gastroenterology
Background:
- Erythromycin is a widely used antibiotic.
- Drug-induced pancreatitis is an uncommon but serious adverse effect.
Observation:
- A 20-year-old female ingested 3g of erythromycin and 6g of acetaminophen.
- Within 40 minutes, she presented with severe abdominal pain, nausea, and vomiting.
Findings:
- Elevated serum amylase and lipase levels confirmed acute pancreatitis.
- The patient recovered fully with supportive treatment, showing no long-term complications.
Implications:
- This case adds to the limited literature on erythromycin-induced pancreatitis.
- Clinicians should consider erythromycin as a potential cause of pancreatitis in patients with relevant exposure.