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The modified biophysical profile: antepartum testing in the 1990s
D A Miller1, Y A Rabello, R H Paul
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Los Angeles County and University of Southern California Women's and Children's Hospital, CA 90033, USA.
Objective:
Our goal was to determine the false-negative and false-positive rates of antepartum testing by use of the modified biophysical profile.
Study Design:
From Jan. 1, 1990, through Dec. 31, 1994, antepartum testing results were gathered prospectively and tabulated monthly. For 1 year, 1991, detailed intrapartum and neonatal data were collected from all women admitted and delivered as a result of an abnormal antepartum test result.
Results:
The false-negative rate of the antepartum testing protocol was 0.8 per 1000 women tested. Sixty percent of those delivered because of an abnormal antepartum test had no evidence of short-term or long-term fetal compromise. False-positive test results led to preterm delivery in 1.5% of those tested before term.
Conclusion:
The false-negative rate of the modified biophysical profile is lower than that of the nonstress test and compares favorably with the false-negative rates of the contraction stress test and the complete biophysical profile. Iatrogenic prematurity resulting from intervention for false positive test results occurred in 1.5% of women tested before 37 weeks.