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Published on: March 27, 2018
Noncardiac surgery in the cardiac patient: what is the question?
1Long Island Jewish Medical Center, New Hyde Park, New York, USA.
Insights
For patients undergoing noncardiac surgery, routine cardiac testing is not supported by evidence. Focus on managing postoperative stress to reduce cardiac events, rather than pre-operative testing.
Area of Science:
- Cardiology
- Perioperative Medicine
Background:
- Patients with coronary artery disease often undergo pre-operative cardiac testing before noncardiac surgery.
- The goal is to reduce adverse cardiac events through prophylactic coronary revascularization.
- Current evidence does not support this approach.
Purpose of the Study:
- To evaluate the effectiveness of routine noninvasive cardiac testing before major noncardiac surgery.
- To determine the optimal strategy for managing cardiac risk in this patient population.
Main Methods:
- This study reviews existing literature and clinical evidence regarding pre-operative cardiac testing.
- It analyzes the causes of perioperative cardiac events, focusing on myocardial oxygen supply and demand imbalances.
Main Results:
- No randomized trials support the use of prophylactic coronary revascularization to reduce adverse events.
- Adverse cardiac events are linked to postoperative stress and catecholamine surges, leading to oxygen supply-demand mismatch.
- Plaque rupture in this context is often secondary, not primary.
Conclusions:
- Preventing excess myocardial oxygen demand post-surgery is more likely to improve outcomes than pre-operative testing.
- Routine noninvasive cardiac testing should be skipped for most patients unless they present with a clinical syndrome of active plaque rupture requiring independent cardiac treatment.
Abstract:
Before having major noncardiac surgery, patients with known or suspected coronary artery disease frequently have noninvasive cardiac testing to better define their cardiac risk. The rationale for this approach is that prophylactic coronary revascularization will significantly reduce the number of adverse cardiac events. No randomized studies support this conclusion. Furthermore, recent studies have suggested that adverse cardiac events result from postoperative stress and excess catecholamine levels, which cause an imbalance between myocardial oxygen supply and demand. Plaque rupture in this setting, if it occurs, is secondary and not primary, in contrast to its pivotal role in spontaneous myocardial infarction. Therefore, improved clinical outcomes are more likely to result from preventing excess oxygen demand after surgery rather than from deciding which tests optimally predict adverse events. The exception is the patient with a clinical syndrome consistent with existing plaque rupture who requires active therapy for the cardiac disease independent of the need for noncardiac surgery. Otherwise, the tests should be skipped and the patient cleared.
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