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Chromonyl-aminosalicylic acid derivatives as possible antimycobacterial agents
M Lácová1, H Stankovicová, Z Odlerová
1Department of Organic Chemistry, Comenius University, Bratislava, Slovakia.
Farmaco (Societa Chimica Italiana : 1989)
|December 1, 1995
Abstract:
N-(2H,3H,4H-4-oxo-6-R1-2-R2O-benzopyran-3-ylidenmethyl) derivatives and imino derivatives of 3-, 4-, 5-aminosalicylic acids were prepared. It was found that some of the synthesized derivatives of 4-aminosalicylic acid are as effective against typical and atypical strains of mycobacteria as isoniazid (INH). Interesting activity of some derivatives against yeast was also found.