Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postmortem diffusion of ingested and aspirated paint thinner

C Fuke1, C L Berry, D J Pounder

  • 1Department of Forensic Medicine, Kagawa Medical School, Japan.

Forensic Science International
|April 23, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations.

Journal of analytical toxicology·2011
Same author

Value of rectal biopsy in paediatric neurology: report of 165 biopsies.

British medical journal·2010
Same author

OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths.

Clinical pharmacology and therapeutics·2010
Same author

A chloroform-related death: analytical and forensic aspects.

Forensic science international·2010
Same author

Who takes alcohol prior to suicide?

Journal of clinical forensic medicine·2004
Same author

Fatal air embolism occurring during consensual intercourse in a non-pregnant female.

Journal of clinical forensic medicine·2004
Same journal

Technical note: Development of a UHPLC-MS/MS method for the analysis of hCG and IGF-I from dried blood spots: A preliminary study.

Forensic science international·2026
Same journal

A novel and robust deep learning model for sibling firearm matching.

Forensic science international·2026
Same journal

Changes in C-reactive protein levels over time in high-temperature environments using postmortem blood.

Forensic science international·2026
Same journal

Insights from the first synthetic cannabinoid clandestine lab dismantled in Brazil.

Forensic science international·2026
Same journal

Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their metabolites in blood and urine using DLLE-LC-MS/MS: application to real forensic case samples.

Forensic science international·2026
Same journal

The revolver halo as a forensic marker: Raman spectroscopic evidence of primer-driven gunshot residue deposition.

Forensic science international·2026
See all related articles

Post-mortem paint thinner diffusion from the stomach or airways is unlikely to affect blood, brain, or liver analysis. Pericardial fluid and gastric contents can identify ethyl acetate and isobutanol, indicating thinner exposure.

Area of Science:

  • Forensic Toxicology
  • Postmortem Chemistry
  • Analytical Chemistry

Background:

  • Paint thinner components, such as toluene, ethyl acetate, and isobutanol, can be relevant in forensic investigations.
  • Understanding postmortem diffusion is crucial for interpreting toxicological findings.

Purpose of the Study:

  • To assess the postmortem diffusion of paint thinner components from gastric residue and airways.
  • To determine the reliability of toxicological samples after potential thinner exposure.

Main Methods:

  • A human cadaver model was used to simulate paint thinner exposure via gastric instillation and tracheal contamination.
  • Samples were collected after 24 hours at room temperature, including blood, pericardial fluid, bile, urine, brainstem, lung, liver, spleen, kidneys, and fat.

Related Experiment Videos

  • Toluene, ethyl acetate, and isobutanol concentrations were analyzed using quantitative methods.

    • Main Results:

    • Toluene diffusion into blood was higher after tracheal instillation than gastric instillation.
    • Isobutanol showed significant diffusion into blood and various tissues, with higher concentrations in the left liver lobe.
    • Ethyl acetate was mostly undetectable in tissues but present in blood and pericardial fluid, especially after tracheal exposure.

    Conclusions:

    • Postmortem diffusion of toluene from gastric or airway sources is unlikely to invalidate femoral blood, brain, or right liver lobe analyses.
    • Analysis of pericardial fluid and gastric contents can help identify ethyl acetate and isobutanol, confirming thinner exposure.