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Related Experiment Videos

Progress on vaccination against Haemonchus contortus

S E Newton1

  • 1Centre for Animal Biotechnology, School of Veterinary Science, University of Melbourne, Parkville, Victoria, Australia.

International Journal for Parasitology
|November 1, 1995
PubMed
Summary
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Vaccination offers a promising alternative to anthelmintics for controlling Haemonchus contortus, especially with rising drug resistance. Research focuses on

Area of Science:

  • Veterinary Parasitology
  • Immunology
  • Molecular Biology

Background:

  • Anthelmintics are the primary method for controlling Haemonchus contortus, but widespread resistance necessitates alternative strategies.
  • Concerns regarding chemical use and manufacturing drive interest in vaccination for parasite control.

Purpose of the Study:

  • To review recent advancements in Haemonchus contortus vaccines.
  • To compare the advantages and disadvantages of 'hidden' versus 'natural' antigen vaccine approaches.

Main Methods:

  • Review of scientific literature on Haemonchus contortus vaccine development.
  • Analysis of vaccination strategies utilizing 'hidden' and 'natural' antigens.

Main Results:

Related Experiment Videos

  • Promising results have been achieved with hidden antigens like H11 (H110D) and H-gal-GP.
  • Natural antigen vaccines offer potential benefits, including immune response boosting via field challenge.

    • Conclusions:

    • Vaccination presents a viable alternative to anthelmintics for Haemonchus contortus control.
    • Both hidden and natural antigen strategies have distinct advantages and disadvantages that warrant further investigation.