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Macrophage activation syndrome in systemic juvenile rheumatoid arthritis successfully treated with cyclosporine
A Ravelli1, F De Benedetti, S Viola
1Clinica Pediatrica, Università di Pavia, Istituto di Ricovero e Cura a Carattere Scientifico S. Matteo, Italy.
The Journal of Pediatrics
|February 1, 1996
Abstract:
A macrophage activation syndrome, possibly related to methotrexate toxicity, developed in a boy with systemic juvenile rheumatoid arthritis. Corticosteroid administration was ineffective, whereas a prompt response to cyclosporine was observed. Two months later, Pneumocystis carinii pneumonia developed.