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Identification of the telomeres on Schistosoma mansoni chromosomes by FISH

H Hirai¹, P T LoVerde

¹Department of Microbiology, School of Medicine, State University of New York at Buffalo 14214, USA.

The Journal of Parasitology

|June 1, 1996

Abstract:

The telomeres (molecular termini) of chromosomes play an important role in maintaining the structural integrity of the chromosome. Using a deoxyoligomer that contains the core sequence TTAGGG, we identified by fluorescence in situ hybridization (FISH) the telomeres on all 8 pairs of Schistosoma mansoni mitotic metaphase chromosomes. Our results indicate that S. mansoni exhibits a telomere sequence typical of other species.

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