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Risk assessment related to veterinary biologicals: side-effects in target animals
1Pfizer Inc. Central Research, Lincoln, Nebraska 68501-0809, USA.
Revue Scientifique Et Technique (International Office of Epizootics)
|December 1, 1995
Summary
Veterinary biologicals can cause side-effects like injection site reactions and immune system effects. Continuous quality improvement and new regulations will ensure safer products for animal health.
Area of Science:
- Veterinary Medicine
- Immunology
- Biotechnology
Background:
- Veterinary biologicals are crucial for animal health but can present adverse effects.
- Established control measures do not entirely eliminate risks associated with large-scale use.
- Understanding these side-effects is vital for product safety and efficacy.
Purpose of the Study:
- To outline common side-effects associated with veterinary biologicals.
- To highlight the importance of quality control and regulatory frameworks.
- To emphasize the role of technological advancements in ensuring product safety.
Main Methods:
- Review of reported side-effects from veterinary biologicals.
- Analysis of factors contributing to adverse events.
- Examination of current regulatory and technological trends.
Main Results:
- Common side-effects include injection site reactions, systemic and allergic reactions, immune system effects, residual pathogenicity, inadequate inactivation, genetic recombination, and contamination.
- These adverse events can occur despite existing control measures.
- Technological advancements and harmonized regulations are key to mitigating risks.
Conclusions:
- Ongoing vigilance and adherence to quality standards are necessary for veterinary biologicals.
- New technologies and updated regulations are essential for a continuous supply of safe products.
- Future efforts should focus on minimizing side-effects and maximizing the benefits of veterinary biologicals.
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