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[Alpha-fetoprotein suppresses keratinocyte proliferation in vitro]
Izvestiia Akademii Nauk. Seriia Biologicheskaia
|January 1, 1996
Abstract:
The influence of alpha-fetoprotein (AFP) on the proliferation of human epidermal keratinocytes in vitro has been studied. AFP (1p microgram/ ml) inhibits the proliferation of keratinocytes cultivated in a serum-free medium. The addition of fetal bovine serum significantly enhances the effect of AFP in this culture. A similar effect of AFP is observed in a medium with a low content of calcium ions.