Structural organization of the cell surface of pathogenic protozoa

The surface of parasitic protozoa plays an important role in the process of their interaction with cells from the host. The present review analyzes the structural organization of the surface of sporozoa, trypanosomatids, Entamoeba and Trichomonas, as evaluated by conventional transmission electron microscopy, cytochemical techniques and freeze-fracture. In most protozoa, no special region of surface membrane is detected. In others, however, special membrane domains have been described. As examples, we can mention the cytostome found in epimastigote forms of Trypanosoma cruzi, the region of attachment of the flagellum to the protozoon body in Trypanosomatidae and Trichomonadidae, and the inner membrane complex of Apicomplexa.