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Right heart failure due to ventricular adiposity: 'adipositas cordis'--an old diagnosis revisited
1Department of Medicine and Anatomical Pathology, Ottawa Civic Hospital, Ontario.
Insights
Severe heart adiposity, or adipositas cordis, involves increased adipose tissue, particularly in the right ventricle. This condition can impair heart function and was a significant factor in a patient's multiorgan failure.
Area of Science:
- Cardiology
- Pathology
- Medical Imaging
Background:
- Adiposity of the heart, characterized by increased epicardial and other adipose tissue, can affect cardiac structure and function.
- While often an incidental autopsy finding, significant adiposity can have clinical relevance.
Observation:
- The case involves a 46-year-old female presenting with multiorgan failure.
- Her condition was secondary to bronchopneumonia, purulent pericarditis, cardiac tamponade, and sepsis.
Findings:
- Severe adiposity of the heart, termed 'adipositas cordis', was identified as a significant contributing factor.
- The increased adipocytes, particularly noted in the right ventricle, may have interposed between myocytes, potentially impairing ventricular mechanics and function.
Implications:
- This case highlights that severe cardiac adiposity can alter the clinical course of patients with critical illnesses.
- Understanding the impact of adipositas cordis is crucial for comprehensive patient management in critical care settings.
Abstract:
Adiposity of the heart is characterized by an increase in the amount of epicardial and other adipose tissue. The most pronounced changes involve the right ventricle. The adipocytes may be interposed between myocytes, and in severe cases the normal mechanics and function of the ventricle are impaired. Adiposity of the heart is usually an incidental finding at autopsy, and only rarely is it of clinical significance. This report describes a 46-year-old female with multiorgan failure secondary to bronchopneumonia, purulent pericarditis, tamponade and sepsis, whose clinical course was altered due to severe adiposity of the heart, so-called 'adipositas cordis'.
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