Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gastric emptying in diabetes

M F Kong1, I A Macdonald, R B Tattersall

  • 1Department of Diabetes, University Hospital Nottingham, UK.

Diabetic Medicine : a Journal of the British Diabetic Association
|February 1, 1996
PubMed
Summary

Gastric emptying rate significantly impacts blood sugar control in diabetes. Modulating gastric emptying could offer a novel strategy for improving glycemic management in diabetic individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Age-related changes in muscle architecture and metabolism in humans: The likely contribution of physical inactivity to age-related functional decline.

Ageing research reviews·2021
Same author

Necessity for a paradigm shift in the treatment of pediatric obesity.

International journal of obesity (2005)·2018
Same author

Salbutamol-induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic-hypoglycaemic clamp in young people with Type 1 diabetes.

Diabetic medicine : a journal of the British Diabetic Association·2018
Same author

Effects of replacing diet beverages with water on weight loss and weight maintenance: 18-month follow-up, randomized clinical trial.

International journal of obesity (2005)·2018
Same author

Editors' note: Omitting obesity treatment leads to poor outcomes, even in those who appear to be metabolically healthy.

International journal of obesity (2005)·2018
Same author

Dietary carbohydrates: a review of international recommendations and the methods used to derive them.

European journal of clinical nutrition·2018

Area of Science:

  • Endocrinology
  • Gastroenterology
  • Metabolic Diseases

Background:

  • Gastric emptying abnormalities are prevalent in diabetes but show weak correlation with gastrointestinal symptoms.
  • Poor glycemic control can exacerbate diabetic gastrointestinal complications, and vice versa.
  • Gastric emptying's role in glycemic variability is an under-recognized factor in diabetes management.

Purpose of the Study:

  • To explore the relationship between gastric emptying and glycemic control in diabetic patients.
  • To investigate the potential of modulating gastric emptying as a therapeutic strategy for diabetes.

Main Methods:

  • Review of existing literature on gastric emptying in Type 1 and Type 2 diabetes.
  • Analysis of the effects of hyperglycemia and hypoglycemia on gastric emptying rates.
  • Exploration of pharmacological interventions targeting gastric emptying.

Main Results:

  • Evidence suggests both accelerated and delayed gastric emptying occur in diabetes.
  • Hyperglycemia demonstrably slows gastric emptying in both Type 1 and Type 2 diabetes.
  • Accelerated gastric emptying may lead to elevated postprandial glucose levels.

Conclusions:

  • Gastric emptying is a significant, yet often overlooked, factor influencing glycemic control in diabetes.
  • Pharmacological delay of gastric emptying presents a potential new avenue for improving postprandial glucose management and overall diabetic control.

Related Experiment Videos