Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flying insects: model systems in exercise physiology

G Wegener1

  • 1Institut für Zoologie, Johannes-Gutenberg-Universität, Mainz, Germany.

Experientia
|May 15, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phylogenetic and functional diverse ANME-1 thrive in Arctic hydrothermal vents.

FEMS microbiology ecology·2022
Same author

Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects.

Neuropharmacology·2021
Same author

Hemisphere-dependent endocannabinoid system activity in prefrontal cortex and hippocampus of the Flinders Sensitive Line rodent model of depression.

Neurochemistry international·2019
Same author

Syringe-feeding as a novel delivery method for accurate individual dosing of probiotics in rats.

Beneficial microbes·2017
Same author

Chronic maternal inflammation or high-fat-feeding programs offspring obesity in a sex-dependent manner.

International journal of obesity (2005)·2017
Same author

[Proteins in early development of the cricket (Acheta domesticus, Orthoptera)].

Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen·2017
Same journal

On the influence of aneurine on the formation of nitrogenic bacterial nodites.

Experientia·2010
Same journal

Around the biochemical activities of the flavobacterium.

Experientia·2010
Same journal

Electron microscopic investigations on cellulose fibers after treatment with ultrasound.

Experientia·2010
Same journal

Reviving scientific life in Hungary.

Experientia·2010
Same journal

A new method for the production of deoxy sugars.

Experientia·2010
Same journal

About the aneine content of the irritated and irritated frog nerves after poisoning with mono-iodoacetic acid.

Experientia·2010
See all related articles

Insect flight muscles efficiently couple energy production and use. Metabolite changes during flight regulate fuel use, with octopamine controlling carbohydrate oxidation via fructose-2,6-bisphosphate.

Area of Science:

  • Biochemistry
  • Insect Physiology
  • Metabolic Regulation

Background:

  • Insect flight is highly energy-intensive, demanding efficient adenosine triphosphate (ATP) hydrolysis and regeneration.
  • Understanding metabolic control is crucial for insect flight performance.

Purpose of the Study:

  • To investigate the metabolic shifts during insect flight.
  • To elucidate the role of key metabolites and signaling molecules in regulating energy metabolism.

Main Methods:

  • In vivo 31P nuclear magnetic resonance (NMR) spectroscopy in locust flight muscle.
  • Measurement of metabolite concentrations (ATP, ADP, AMP, Pi, F2,6P2).

Main Results:

  • Flight caused minimal ATP decrease but significant increases in ADP, AMP, and Pi.

Related Experiment Videos

  • Glycolytic flux decreased during prolonged flight, linked to an 80% reduction in fructose-2,6-bisphosphate (F2,6P2) within 15 minutes.
  • Octopamine stimulated F2,6P2 synthesis, suggesting a role in metabolic control.

    • Conclusions:

    • Metabolite changes (AMP, Pi) activate glycolysis, while F2,6P2 levels decrease during prolonged flight, facilitating a shift from carbohydrate to lipid fuel.
    • Octopamine and F2,6P2 are key components in controlling carbohydrate oxidation and integrating insect flight metabolism.