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Core body temperature during menopausal hot flushes

R R Freedman1, S Woodward

  • 1Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA.

Fertility and Sterility
|June 1, 1996
PubMed
Summary
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Core body temperature increases precede most menopausal hot flushes, suggesting a role in triggering this heat-loss event. Ingested radiotelemetry pills accurately measured these temperature changes.

Area of Science:

  • Physiology
  • Women's Health
  • Thermoregulation

Background:

  • Menopausal hot flushes are common and disruptive vasomotor symptoms.
  • The precise physiological triggers of hot flushes remain incompletely understood.
  • Accurate measurement of core body temperature is crucial for understanding thermoregulatory events.

Purpose of the Study:

  • To compare core body temperature measurements using an ingested radiotelemetry pill versus a rectal thermometer during menopausal hot flushes.
  • To investigate the temporal relationship between core body temperature changes and the onset of hot flushes.

Main Methods:

  • Eight postmenopausal women with frequent hot flushes participated in a controlled laboratory study.
  • Core body temperature was continuously monitored using an ingested radiotelemetry pill and a rectal probe during sleep.

Related Experiment Videos

  • Hot flushes were objectively identified by increases in sternal skin conductance levels.

    • Main Results:

    • Thirty-seven hot flushes were detected during the study period.
    • Significant core body temperature increases, measured by the radiotelemetry pill, preceded 24 of the hot flushes.
    • Rectal temperature measurements did not show significant changes preceding the hot flushes.

    Conclusions:

    • Elevations in core body temperature appear to precede the majority of menopausal hot flushes.
    • These core body temperature increases may act as a trigger for the heat-loss response characteristic of hot flushes.
    • Ingested radiotelemetry offers a viable method for measuring core body temperature during such physiological events.