Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extraperitoneal laparoscopic para-aortic lymph node dissection

S A Vasilev1, K F McGonigle

  • 1Department of Gynecology, City of Hope National Medical Center, Duarte, California 91010, USA.svasilev@smtplink.coh.org

Gynecologic Oncology
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uterine effects of tamoxifen: a prospective study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2006
Same author

The use of continuous infusion topotecan in persistent and recurrent ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2003
Same author

Ovarian cancer metastatic to the brain: what is the optimal management?

Journal of surgical oncology·2001
Same author

Endometrial cancer: recent developments in evaluation and treatment.

Oncology (Williston Park, N.Y.)·2000
Same author

An experience with estrogen replacement therapy in breast cancer survivors.

International journal of fertility and women's medicine·1999
Same author

Ovarian histopathology in breast cancer patients receiving tamoxifen.

Gynecologic oncology·1999

A novel extraperitoneal laparoscopic technique for para-aortic lymph node dissection was developed and tested in pigs and humans. This minimally invasive approach shows feasibility for cancer staging and potential for reduced complications.

Area of Science:

  • Minimally Invasive Surgery
  • Surgical Oncology
  • Laparoscopic Techniques

Background:

  • Extraperitoneal cervical cancer staging is preferred over transperitoneal approaches.
  • Para-aortic lymph node dissection is crucial for accurate cancer staging.
  • Existing laparoscopic techniques may have limitations.

Purpose of the Study:

  • To develop and evaluate an entirely extraperitoneal laparoscopic technique for para-aortic lymph node dissection.
  • To assess the feasibility and safety of this novel approach in a preclinical model and human subjects.
  • To explore the potential advantages of adhesion avoidance and outpatient procedures.

Main Methods:

  • Development of a laparoscopic extraperitoneal technique using latex balloon dissection technology.

Related Experiment Videos

  • Creation of a retroperitoneal space via a left flank incision and CO2 pneumoretroperitoneum.
  • Application in a pig model for technique refinement followed by bilateral node sampling in human subjects.

    • Main Results:

    • Successful development and application of the extraperitoneal laparoscopic technique in pigs and humans.
    • Achieved excellent bilateral retroperitoneal exposure and complete lymph node dissection from renal to iliac vessels in pigs.
    • In human subjects, a mean of 5 lymph nodes were sampled with minimal blood loss (<50 cc) and no intra- or postoperative complications.

    Conclusions:

    • Laparoscopic extraperitoneal para-aortic access and node sampling is a feasible and safe procedure.
    • This technique may offer advantages of adhesion avoidance, similar to extraperitoneal laparotomy.
    • Further studies are warranted to determine the full extent of dissection possible and its clinical utility.