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Localization of the human vascular endothelial growth factor gene, VEGF, at chromosome 6p12
M H Wei1, N C Popescu, M I Lerman
1Biological Carcinogenesis and Development Program, National Cancer Institute-Frederick Cancer Research and Development Center, MD 21702, USA.
Human Genetics
|June 1, 1996
Abstract:
Using overlapping cosmids representing the vascular endothelial growth factor (VEGF) locus, the VEGF gene was mapped by fluorescence in situ hybridization to chromosome 6p12. This localization permits linkage analysis and the identification of gene interaction in the region, as well as alterations of the VEGF structure or expression in cancer cells with chromosome abnormalities.